Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

Distinct Classes of Phosphatidylinositol 3′-Kinases Are Involved in Signaling Pathways That Control Macroautophagy in HT-29 Cells

Anne Petiot, Éric Ogier‐Denis, Edward F. C. Blommaart et al. · Journal of Biological Chemistry · 2000 · 1.2K citations · Full text

Life Sciences, Cell Biology, Oncology +16

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

Päivi J. Miettinen, Joel E. Berger, Juanito J. Meneses et al. · Nature · 1995 · 1K citations

Life Sciences, Cell Biology, Developmental Biology +14

Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model.

Neil I. Goldstein, Marie Prewett, Kazys Zuklys et al. · PubMed · 1995 · 790 citations

Medicine, Oncology, Pharmacology +14

Phase II Trial of ZD1839 in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Ezra E.W. Cohen, Fred Rosen, Walter M. Stadler et al. · Journal of Clinical Oncology · 2003 · 607 citations

Medicine, Oncology, Pharmacotherapy +13

The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase.

Noreen Luetteke, Harmony K. Phillips, Ting Qiu et al. · Genes & Development · 1994 · 438 citations · Full text

Life Sciences, Genetics, Molecular Biology +13