Eilyn R. Lacy

p27 binds cyclin–CDK complexes through a sequential mechanism involving binding-induced protein folding

Eilyn R. Lacy, Igor Filippov, William S. Lewis et al. · Nature Structural & Molecular Biology · 2004 · 301 citations

Binding-induced Protein Folding, Cyclin–cdk Complexes, Protein Function +10

Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α

David J. Shealy, Ann Cai, Kim Staquet et al. · mAbs · 2010 · 239 citations · Full text

Immunology, Immune Regulation, Pathology +22

Structure-based engineering of a monoclonal antibody for improved solubility

Sheng‐Jiun Wu, Jinquan Luo, Karyn T. O’Neil et al. · Protein Engineering Design and Selection · 2010 · 180 citations

Thrombogenic collagen-mimetic peptides: Self-assembly of triple helix-based fibrils driven by hydrophobic interactions

Mabel A. Cejas, William A. Kinney, Cailin Chen et al. · Proceedings of the National Academy of Sciences · 2008 · 168 citations · Full text

Tissue Engineering, Protein Assembly, Peptide Engineering +17

An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations

Omid Vafa, Gary L. Gilliland, Randall J. Brezski et al. · Methods · 2013 · 149 citations

Engineered Fc Variant, Signal Transduction, Autoimmune Disease +12