Simone Schubert

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

Sebastian Bender, Yujie Tang, Anders M. Lindroth et al. · Cancer Cell · 2013 · 842 citations · Full text

Medicine, Genetics, Molecular Biology +13

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors

Siddhartha S. Mitra, Abdullah H. Feroze, Jie Liu et al. · Science Translational Medicine · 2017 · 425 citations

Medicine, Immunology, Oncology +17

BET Bromodomain Inhibition of <i>MYC</i> -Amplified Medulloblastoma

Pratiti Bandopadhayay, Guillaume Bergthold, Brian T. Nguyen et al. · Clinical Cancer Research · 2013 · 351 citations · Full text

Medicine, Oncology, Pharmacology +13

MRI Surrogates for Molecular Subgroups of Medulloblastoma

Sébastien Perreault, Vijay Ramaswamy, Achal S. Achrol et al. · American Journal of Neuroradiology · 2014 · 322 citations · Full text

Medicine, Oncology, Radiology +17

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition

Yujie Tang, Sharareh Gholamin, Simone Schubert et al. · Nature Medicine · 2014 · 314 citations · Full text

Life Sciences, Genetics, Molecular Biology +15