David J. Nash

Design and Synthesis of <i>trans</i>-<i>N</i>-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011):  A Potent and Selective Dopamine D₃ Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

Geoffrey Stemp, Tracey Ashmeade, Clive L. Branch et al. · Journal of Medicinal Chemistry · 2000 · 129 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Evidence for antagonist activity of the dopamine D3 receptor partial agonist, BP 897, at human dopamine D3 receptor

Martyn Wood, Izzy Boyfield, David J. Nash et al. · European Journal of Pharmacology · 2000 · 64 citations

Medicine, Neuroscience, Pharmacology +15

Design and Synthesis of 2-Naphthoate Esters as Selective Dopamine D₄Antagonists

Izzy Boyfield, Thomas H. Brown, Martyn C. Coldwell et al. · Journal of Medicinal Chemistry · 1996 · 50 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Novel 1,2,3,4-tetrahydroisoquinolines with high affinity and selectivity for the dopamine D3 receptor

Nigel Austin, Kim Y. Avenell, Izzy Boyfield et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 22 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

N-(substituted-phenyl) piperazines: antagonists with high binding and functional selectivity for dopamine D4 receptors

Izzy Boyfield, Martyn C. Coldwell, Michael S. Hadley et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 18 citations

Medicine, Medicinal Chemistry, Pharmacology +13