Derek Ng Tang

CTLA-4 blockade increases IFNγ-producing CD4 ⁺ ICOS ^hi cells to shift the ratio of effector to regulatory T cells in cancer patients

Chrysoula I. Liakou, Ashish M. Kamat, Derek Ng Tang et al. · Proceedings of the National Academy of Sciences · 2008 · 538 citations · Full text

Medicine, Immunology, Oncology +17

Anti-CTLA-4 therapy results in higher CD4 ⁺ ICOS ^hi T cell frequency and IFN-γ levels in both nonmalignant and malignant prostate tissues

Hong Chen, Chrysoula I. Liakou, Ashish M. Kamat et al. · Proceedings of the National Academy of Sciences · 2009 · 216 citations · Full text

Life Sciences, Immunology, Oncology +17

Increased Frequency of ICOS+ CD4 T Cells as a Pharmacodynamic Biomarker for Anti-CTLA-4 Therapy

Derek Ng Tang, Yu Shen, Jingjing Sun et al. · Cancer Immunology Research · 2013 · 198 citations · Full text

Life Sciences, Immunology, Pharmacology +17

TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines

Xinzhen Yang, Moses O. Gold, Derek Ng Tang et al. · Proceedings of the National Academy of Sciences · 1997 · 171 citations

Life Sciences, Cell Biology, Molecular Biology +15

NY-ESO-1 DNA Vaccine Induces T-Cell Responses That Are Suppressed by Regulatory T Cells

Sacha Gnjatic, Nasser K. Altorki, Derek Ng Tang et al. · Clinical Cancer Research · 2009 · 78 citations · Full text

Medicine, Immunology, Oncology +17