Structural definition of a conserved neutralization epitope on HIV-1 gp120

Tongqing Zhou, Ling Xu, Barna Dey, +13

Nature

Virus StructureConserved Neutralization EpitopeHuman RetrovirusImmunologyAntiviral Response +6

Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors

Mattia Bonsignori, Kwan-Ki Hwang, Xi Chen, +31

Journal of Virology

GeneticsImmunologyViral Structural ProteinImmunotherapyViral Evolution +15

Highly Stable Trimers Formed by Human Immunodeficiency Virus Type 1 Envelope Glycoproteins Fused with the Trimeric Motif of T4 Bacteriophage Fibritin

Xinzhen Yang, Juliette Lee, Erin M. Mahony, +3

Journal of Virology

Viral ReplicationGlycobiologyMolecular BiologyViral Structural ProteinVirus Structure +16

Improved Elicitation of Neutralizing Antibodies against Primary Human Immunodeficiency Viruses by Soluble Stabilized Envelope Glycoprotein Trimers

Xinzhen Yang, Richard T. Wyatt, Joseph Sodroski

Journal of Virology

Stoichiometry of Envelope Glycoprotein Trimers in the Entry of Human Immunodeficiency Virus Type 1

Xinzhen Yang, Svetla Kurteva, Xinping Ren, +1

Journal of Virology

Virus StructureViral ReplicationHiv-1 EntryEnv TrimersEnvelope Glycoprotein Trimers +12

TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines

Xinzhen Yang, Moses O. Gold, Derek Ng Tang, +4

Proceedings of the National Academy of Sciences

Characterization of Stable, Soluble Trimers Containing Complete Ectodomains of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins

Xinzhen Yang, Michael Farzan, Richard T. Wyatt, +1

Journal of Virology

Modifications That Stabilize Human Immunodeficiency Virus Envelope Glycoprotein Trimers in Solution

Xinzhen Yang, Lauren Florin, Michael Farzan, +4

Journal of Virology

Functional UnitBiochemistryProtein FoldingNatural SciencesHuman Retrovirus +13

Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer

Youdong Mao, Liping Wang, Christopher Gu, +5

Nature Structural & Molecular Biology

Subunit OrganizationHuman RetrovirusMolecular BiologyViral Structural ProteinHiv +1

Thermodynamics of Binding of a Low-Molecular-Weight CD4 Mimetic to HIV-1 gp120

Arne Schön, Navid Madani, Jeffrey C. Klein, +6

Biochemistry