SD-208, a Novel Transforming Growth Factor β Receptor I Kinase Inhibitor, Inhibits Growth and Invasiveness and Enhances Immunogenicity of Murine and Human Glioma Cells<b><i>In vitro</i></b>and<b><i>In vivo</i></b>

Martin Uhl, Steffen Aulwurm, Jörg Wischhusen, +12

Cancer Research

Pharmacologic Inhibition of the TGF-β Type I Receptor Kinase Has Anabolic and Anti-Catabolic Effects on Bone

Khalid S. Mohammad, Carol G. Chen, Guive Balooch, +15

PLoS ONE

Mutants in a yeast Ran binding protein are defective in nuclear transport.

Gabriel Schlenstedt, Darren H. Wong, Deanna M. Koepp, +1

The EMBO Journal

Natural SciencesMolecular BiologyYeastNuclear OrganizationMolecular Genetics +5

Dynamic localization of the nuclear import receptor and its interactions with transport factors.

Deanna M. Koepp, Darren H. Wong, Anita H. Corbett, +1

The Journal of Cell Biology

Molecular BiologyCellular PhysiologyNuclear EnvelopeGtpase RanSecretory Pathway +17

Inhibition of Transforming Growth Factor β Signaling Reduces Pancreatic Adenocarcinoma Growth and Invasiveness

N. J. Gaspar, Lingyun Li, Ann M. Kapoun, +12

Molecular Pharmacology

Interaction between the Small GTPase Ran/Gsp1p and Ntf2p Is Required for Nuclear Transport

Darren H. Wong, Anita H. Corbett, Helen M. Kent, +2

Molecular and Cellular Biology

Nuclear DataGeneticsMolecular BiologyMolecular GeneticsTranscriptional Regulation +14

Biochemical Studies of Zmpste24-deficient Mice

Gordon Leung, Walter K. Schmidt, Martin O. Bergö, +6

Journal of Biological Chemistry

Inhibiting TGF-β signaling restores immune surveillance in the SMA-560 glioma model

Thomas-Toan Tran, Martin Uhl, Ying Jing, +19

Neuro-Oncology

Restores Immune SurveillanceImmune RegulationImmunologyImmunoeditingHigh-grade Gliomas +20

Yeast clathrin has a distinctive light chain that is important for cell growth.

Linda A. Silveira, Darren H. Wong, Frank R. Masiarz, +1

The Journal of Cell Biology

Fungal Cell BiologyGeneticsMolecular BiologyMolecular GeneticsCell Growth +18

Studies with Recombinant <i>Saccharomyces cerevisiae</i> CaaX Prenyl Protease Rce1p

Julia M. Dolence, Lance E. Steward, E. Kurt Dolence, +2

Biochemistry