Jonathan Pollock

Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo

Dmitry Borkin, Shihan He, Hongzhi Miao et al. · Cancer Cell · 2015 · 402 citations · Full text

Medicine, Oncology, Pharmacology +9

Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein–Ligand Complexes

Jonathan Pollock, Dmitry Borkin, George Lund et al. · Journal of Medicinal Chemistry · 2015 · 102 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase

Kristen A. Baltgalvis, Kelsey N. Lamb, Kent T. Symons et al. · Nature · 2024 · 102 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

Shihan He, Timothy J. Senter, Jonathan Pollock et al. · Journal of Medicinal Chemistry · 2014 · 93 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein–Protein Interaction between Menin and Mixed Lineage Leukemia (MLL)

Dmitry Borkin, Jonathan Pollock, Katarzyna Kempińska et al. · Journal of Medicinal Chemistry · 2016 · 73 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17