Xunyi Luo

Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress

Kathrin Zaugg, Yi Yao, Patrick T. Reilly et al. · Genes & Development · 2011 · 494 citations · Full text

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1<i>R</i>,2<i>S</i>)-2-(3-((<i>E</i>)-4-(((<i>cis</i>)-2,6-Dimethylmorpholino)methyl)styryl)-1<i>H</i>-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

Peter B. Sampson, Yong Liu, Bryan Forrest et al. · Journal of Medicinal Chemistry · 2014 · 166 citations · Full text

The Discovery of PLK4 Inhibitors: (<i>E</i>)-3-((1<i>H</i>-Indazol-6-yl)methylene)indolin-2-ones as Novel Antiproliferative Agents

Radoslaw S. Laufer, Bryan Forrest, Sze-Wan Li et al. · Journal of Medicinal Chemistry · 2013 · 71 citations · Full text

Molecular Biology, Pharmacotherapy, Chemical Biology +18

Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides

Radoslaw S. Laufer, Grace Ng, Yong Liu et al. · Bioorganic & Medicinal Chemistry · 2014 · 38 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +10

γ-Synuclein Is an Adipocyte-Neuron Gene Coordinately Expressed with Leptin and Increased in Human Obesity , ,3

Pieter J. Oort, Trina A. Knotts, Michel Grino et al. · Journal of Nutrition · 2008 · 35 citations

Obesity, Metabolic Syndrome, Neurodegenerative Diseases +15