Michael B. Lilly

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

Matthew R. Janes, Jose J. Limon, Lomon So et al. · Nature Medicine · 2010 · 338 citations · Full text

Medicine, Oncology, Pharmacology +14

Pim‐1 kinase promotes inactivation of the pro‐apoptotic Bad protein by phosphorylating it on the Ser¹¹² gatekeeper site

Teija L. T. Aho, Jouko Sandholm, Katriina Peltola et al. · FEBS Letters · 2004 · 320 citations

Life Sciences, Cell Biology, Molecular Biology +17

The PIM-2 Kinase Phosphorylates BAD on Serine 112 and Reverses BAD-induced Cell Death

Bin Yan, Marina Zemskova, Sheldon L. Holder et al. · Journal of Biological Chemistry · 2003 · 259 citations · Full text

Life Sciences, Cell Biology, Apoptosis +12

Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival

Kyu-Tae Kim, Kristin Baird, Joon-Young Ahn et al. · Blood · 2004 · 229 citations

Life Sciences, Cell Biology, Molecular Biology +11

Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase

Sheldon L. Holder, Marina Zemskova, Chao Zhang et al. · Molecular Cancer Therapeutics · 2007 · 184 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9