Kyu-Tae Kim

Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML

Annahita Sallmyr, Jinshui Fan, Kamal Datta et al. · Blood · 2008 · 306 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +15

Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival

Kyu-Tae Kim, Kristin Baird, Joon-Young Ahn et al. · Blood · 2004 · 229 citations

Life Sciences, Cell Biology, Molecular Biology +11

Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways

Obdulio Piloto, Melissa A. Wright, Patrick A. Brown et al. · Blood · 2006 · 199 citations · Full text

Medicine, Cancer Biology, Pharmacology +14

IMC-EB10, an Anti-FLT3 Monoclonal Antibody, Prolongs Survival and Reduces Nonobese Diabetic/Severe Combined Immunodeficient Engraftment of Some Acute Lymphoblastic Leukemia Cell Lines and Primary Leukemic Samples

Obdulio Piloto, Bao Nguyen, David Huso et al. · Cancer Research · 2006 · 44 citations · Full text

Medicine, Oncology, Pharmacology +11

FLT3/ITD Mutation Signaling Includes Suppression of SHP-1

Peili Chen, Mark J. Levis, Patrick A. Brown et al. · Journal of Biological Chemistry · 2004 · 42 citations · Full text

Life Sciences, Genetics, Molecular Biology +17