Jane E. Moore

Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies

Bernard Barlaam, Robert Casella, Justin Cidado et al. · Journal of Medicinal Chemistry · 2020 · 104 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis of Highly Substituted Pyridazines through Alkynyl Boronic Ester Cycloaddition Reactions

Matthew Helm, Jane E. Moore, Andrew Plant et al. · Angewandte Chemie International Edition · 2005 · 90 citations

Natural Sciences, Chemistry, Organic Chemistry +10

Investigation of the scope of a [3+2] cycloaddition approach to isoxazole boronic esters

Jane E. Moore, Mark W. Davies, Katharine M. Goodenough et al. · Tetrahedron · 2005 · 84 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Fluorous Synthesis of ¹⁸F Radiotracers with the [¹⁸F]Fluoride Ion: Nucleophilic Fluorination as the Detagging Process

Romain Béjot, Thomas Fowler, Laurence Carroll et al. · Angewandte Chemie International Edition · 2008 · 68 citations

Natural Sciences, Chemistry, Nuclear Medicine +11

Pyrimidinone Nicotinamide Mimetics as Selective Tankyrase and Wnt Pathway Inhibitors Suitable for in Vivo Pharmacology

Jeffrey W. Johannes, Lynsie Almeida, Bernard Barlaam et al. · ACS Medicinal Chemistry Letters · 2015 · 65 citations

Medicine, Oncology, Pharmacology +14