MicroRNA Expression Profiles Associated With Prognosis and Therapeutic Outcome in Colon Adenocarcinoma

Aaron J. Schetter, Suet Yi Leung, Jane J. Sohn, +11

JAMA

Association analysis identifies 65 new breast cancer risk loci

Kyriaki Michailidou, Sara Lindström, Joe Dennis, +75

Nature

EpidemiologyBreast OncologyCancer RiskEpidemiology Of CancerGenetic Epidemiology +6

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1

Marjolijn J. L. Ligtenberg, Roland P. Kuiper, Tsun Leung Chan, +15

Nature Genetics

Heritable Somatic MethylationSomatic VariantMendelian DisorderGenetic DisorderMedicine +7

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

Kai Wang, Junsuo Kan, Siu Tsan Yuen, +18

Nature Genetics

Identifies Frequent MutationSomatic VariantMolecular SubtypesGastrointestinal OncologyTumor Heterogeneity +9

Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors

Cynthia Kosinski, Vivian Li, Annie S Y Chan, +9

Proceedings of the National Academy of Sciences

Adult Stem CellSignaling PathwayCell RegulationHuman Colon TopsBone Morphogenic Protein +14

Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.

Siu Tsan Yuen, Helen Davies, Tsun Leung Chan, +11

PubMed

GeneticsPathologyPhenotypic PatternsTumor BiologyFap Adenomas +16

BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas.

Tsun Leung Chan, Wei Zhao, Suet Yi Leung, +1

PubMed

OncologyBraf MutationColorectal Hyperplastic PolypsGastrointestinal OncologyMedicine +13

Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer

Tsun Leung Chan, Siu Tsan Yuen, Chi Kwan Kong, +8

Nature Genetics

MedicineGeneticsPathologyColorectal CancerCancer Genetics +2

Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

Marlies Kempers, Roland P. Kuiper, Charlotte W. Ockeloen, +42

The Lancet Oncology

Cancer RiskMedicineColorectal CancerPathologyGynecology +4

Mutations of PIK3CAin gastric adenocarcinoma

Vivian Li, Chi Wai Wong, Tsun Leung Chan, +7

BMC Cancer