Annie S Y Chan

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer

Kai Wang, Siu Tsan Yuen, Jiangchun Xu et al. · Nature Genetics · 2014 · 1K citations

Whole-genome Sequencing, Somatic Variant, Tumor Heterogeneity +12

Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors

Cynthia Kosinski, Vivian Li, Annie S Y Chan et al. · Proceedings of the National Academy of Sciences · 2007 · 574 citations · Full text

Adult Stem Cell, Signaling Pathway, Cell Regulation +16

Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.

Siu Tsan Yuen, Helen Davies, Tsun Leung Chan et al. · PubMed · 2002 · 411 citations

Genetics, Pathology, Phenotypic Patterns +18

hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability.

Suet Yi Leung, Siu Tsan Yuen, Lap Ping Chung et al. · PubMed · 1999 · 370 citations

High-frequency Microsatellite Instability, Genetics, Hmlh1 Expression +16

RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation

Helen H.N. Yan, Jeffrey C W Lai, Siu Lun Ho et al. · Gut · 2016 · 198 citations