Claudia Heuser

Tumor-Specific T Cell Activation by Recombinant Immunoreceptors: CD3ζ Signaling and CD28 Costimulation Are Simultaneously Required for Efficient IL-2 Secretion and Can Be Integrated Into One Combined CD28/CD3ζ Signaling Receptor Molecule

Andreas Hombach, Anja Wieczarkowiecz, Thomas Marquardt et al. · The Journal of Immunology · 2001 · 294 citations · Full text

Life Sciences, Immunology, Oncology +17

T Cell Activation by Antibody-Like Immunoreceptors: Increase in Affinity of the Single-Chain Fragment Domain above Threshold Does Not Increase T Cell Activation against Antigen-Positive Target Cells but Decreases Selectivity

Markus Chmielewski, Andreas Hombach, Claudia Heuser et al. · The Journal of Immunology · 2004 · 265 citations · Full text

Life Sciences, Biotechnology, Immunology +16

T-cell activation by recombinant receptors: CD28 costimulation is required for interleukin 2 secretion and receptor-mediated T-cell proliferation but does not affect receptor-mediated target cell lysis.

Andreas Hombach, Dagmar Sent, Christophe Schneider et al. · PubMed · 2001 · 115 citations

Life Sciences, Cell Biology, Immunology +17

T Cell Activation by Antibody-Like Immunoreceptors: The Position of the Binding Epitope within the Target Molecule Determines the Efficiency of Activation of Redirected T Cells

Andreas Hombach, Verena Schildgen, Claudia Heuser et al. · The Journal of Immunology · 2007 · 106 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Dermal Fibroblasts Sustain Proliferation of Activated T Cells via Membrane-Bound Interleukin-15 upon Long-Term Stimulation with Tumor Necrosis Factor-α

Anna Kapsokefalou, Claudia Heuser, Hinrich Abken et al. · Journal of Investigative Dermatology · 2001 · 70 citations · Full text

Life Sciences, Cell Biology, Immunology +13