Concepedia
Statistics
Publications
17
Citations
1.6K
H-Index
15
Active since
1994
Affiliations
Xencor (United States)(Current)
University of Southern California
University of Toronto
Irene Leung is an author at Xencor (United States) specializing in medicine, immunology, and immunotherapy.
Top concepts
MedicineImmunologyCell BiologyImmunotherapyAutoimmunityT Cell ImmunityImmune FunctionImmune RegulationImmune SurveillanceAntibody Engineering
Publications per year
1994–2023
Enhanced antibody half-life improves in vivo activity
Jonathan Zalevsky, Aaron K. Chamberlain, Holly M. Horton et al. · Nature Biotechnology · 2010 · 625 citations · Full text
Antibody Half-life Improves, Immunology, Antibody Screening +5
Antibody-Mediated Coengagement of FcγRIIb and B Cell Receptor Complex Suppresses Humoral Immunity in Systemic Lupus Erythematosus
Holly M. Horton, Seung Y. Chu, Elizabeth Ortiz et al. · The Journal of Immunology · 2011 · 141 citations
Adaptive Immune System, Humoral Response, Immune Regulation +27
Dimerization via Tandem Leucine Zippers Is Essential for the Activation of the Mitogen-activated Protein Kinase Kinase Kinase, MLK-3
Irene Leung, Norman J. Lassam · Journal of Biological Chemistry · 1998 · 128 citations · Full text
Mixed Lineage, Molecular Biology, Signaling Pathway +16
Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro
Marjorie Robbins, Mingjie Li, Irene Leung et al. · Nature Biotechnology · 2006 · 102 citations
Immunology, Small Rna, Stable Expression +5
The impact of Fc engineering on an anti-CD19 antibody: increased Fcγ receptor affinity enhances B-cell clearing in nonhuman primates
Jonathan Zalevsky, Irene Leung, Sher Karki et al. · Blood · 2008 · 101 citations · Full text
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