Adam J. Simon

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

Leslie M. Shaw, Hugo Vanderstichele, Małgorzata Knapik-Czajka et al. · Annals of Neurology · 2009 · 2.1K citations · Full text

Structure-Based Design of Potent and Selective Cell-Permeable Inhibitors of Human β-Secretase (BACE-1)

Shawn J. Stachel, Craig A. Coburn, Thomas G. Steele et al. · Journal of Medicinal Chemistry · 2004 · 273 citations · Full text

Protein Secretion, Drug Target, Cell Culture +16

Elevated Cerebrospinal Fluid BACE1 Activity in Incipient Alzheimer Disease

Henrik Zetterberg, Ulf Andréasson, Oskar Hansson et al. · Archives of Neurology · 2008 · 222 citations

A novel pathway for amyloid precursor protein processing

Erik Portelius, Eric A. Price, Gunnar Brinkmalm et al. · Neurobiology of Aging · 2009 · 168 citations

Alzheimer's Disease, Biochemistry, Natural Sciences +5

Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid‐β oligomers

Sam Gandy, Adam J. Simon, John Steele et al. · Annals of Neurology · 2010 · 139 citations