Ajinkya S. Kawale

Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death

Hui Jiang, Xiaoyu Xue, Swarupa Panda et al. · The EMBO Journal · 2019 · 257 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Tumor cell escape from therapy-induced senescence

Tareq Saleh, Liliya Tyutyunyk‐Massey, Graeme Murray et al. · Biochemical Pharmacology · 2018 · 175 citations

Medicine, Cancer Biology, Oncology +14

DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation

Youngho Kwon, Heike I. Rösner, Weixing Zhao et al. · Nature Communications · 2023 · 68 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Unprocessed genomic uracil as a source of DNA replication stress in cancer cells

Sneha Saxena, Christopher S. Nabel, Turner W. Seay et al. · Molecular Cell · 2024 · 40 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +16

APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability

Ajinkya S. Kawale, Xiaojuan Ran, Parasvi S. Patel et al. · Science Advances · 2024 · 37 citations · Full text

Life Sciences, Molecular Biology, Oncology +17