Ruicheng Yang

SARS-CoV-2 M ^pro inhibitors with antiviral activity in a transgenic mouse model

Jingxin Qiao, Yueshan Li, Rui Zeng et al. · Science · 2021 · 439 citations · Full text

Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor

Yueshan Li, Liting Zhang, Yifei Wang et al. · Nature Communications · 2022 · 92 citations · Full text

A new generation Mpro inhibitor with potent activity against SARS-CoV-2 Omicron variants

Chong Huang, Huiping Shuai, Jingxin Qiao et al. · Signal Transduction and Targeted Therapy · 2023 · 79 citations · Full text

Discovery of 3,4-Dihydrobenzo[<i>f</i>][1,4]oxazepin-5(2<i>H</i>)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects

Yueshan Li, Liting Zhang, Ruicheng Yang et al. · Journal of Medicinal Chemistry · 2022 · 21 citations · Full text

From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases

Liting Zhang, Yueshan Li, Chenyu Tian et al. · Journal of Medicinal Chemistry · 2023 · 16 citations · Full text