Tumor-derived exosomal HMGB1 fosters hepatocellular carcinoma immune evasion by promoting TIM-1+ regulatory B cell expansion

Linsen Ye, Qi Zhang, Yusheng Cheng, +11

Journal for ImmunoTherapy of Cancer

STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2

Liting Zhang, Congqing Jiang, Yunhong Zhong, +18

Nature Cell Biology

Energy MetabolismBiochemistryAerobic GlycolysisCell SignalingNatural Sciences +9

Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling

Yibo Zuo, Qian Feng, Lincong Jin, +11

Nature Communications

Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome

Liting Zhang, Jin Liu, Liping Qian, +9

PLoS Pathogens

Rna Virus InfectionImmunologyImmune RegulationInnate ImmunityImmune System +18

ADP-ribosyltransferase PARP11 modulates the interferon antiviral response by mono-ADP-ribosylating the ubiquitin E3 ligase β-TrCP

Tingting Guo, Yibo Zuo, Liping Qian, +11

Nature Microbiology

Adp-ribosyltransferase Parp11Viral ReplicationMolecular VirologyInterferon Antiviral ResponseNatural Sciences +7

Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense

Yukang Yuan, Ying Miao, Liping Qian, +15

Molecular Cell

Molecular VirologyImmunologyAntiviral ResponseVirologyVirus-host Interaction +3

Genome-wide analysis of the DREB family genes and functional identification of the involvement of BrDREB2B in abiotic stress in wucai (Brassica campestris L.)

Ying Wu, Liting Zhang, Libing Nie, +8

BMC Genomics

Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon

Lemin Li, Guanghui Qian, Yibo Zuo, +7

Journal of Biological Chemistry

mascRNA and its parent lncRNA MALAT1 promote proliferation and metastasis of hepatocellular carcinoma cells by activating ERK/MAPK signaling pathway

Shu‐Juan Xie, Li‐Ting Diao, Nan Cai, +12

Cell Death Discovery

Upregulation of sestrin-2 expression protects against endothelial toxicity of angiotensin II

Yi Lao, Feng Li, Yuan Yong, +5

Cell Biology and Toxicology

ImmunologyCardiovascular PharmacologyCell DeathCardiovascular ToxicityEndothelial Toxicity +19