Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis

Xuelian Xiong, Henry Kuang, Sahar Ansari, +27

Molecular Cell

Cell LineageSystems BiologySingle Cell SequencingMedicineLiver Physiology +10

Activation of Natural Killer T Cells Promotes M2 Macrophage Polarization in Adipose Tissue and Improves Systemic Glucose Tolerance via Interleukin-4 (IL-4)/STAT6 Protein Signaling Axis in Obesity

Yewei Ji, Shengyi Sun, Aimin Xu, +7

Journal of Biological Chemistry

InflammationMetabolic SyndromeObesityCytokineT-regulatory Cell +9

Designing a retrievable and scalable cell encapsulation device for potential treatment of type 1 diabetes

Duo An, Alan Chiu, James A. Flanders, +16

Proceedings of the National Academy of Sciences

Short Term High Fat Diet Challenge Promotes Alternative Macrophage Polarization in Adipose Tissue via Natural Killer T Cells and Interleukin-4

Yewei Ji, Shengyi Sun, Sheng Xia, +3

Journal of Biological Chemistry

ObesityMetabolic SyndromeInflammationCytokineImmune Cell Development +12

Developing robust, hydrogel-based, nanofiber-enabled encapsulation devices (NEEDs) for cell therapies

Duo An, Yewei Ji, Alan Chiu, +6

Biomaterials

Tissue EngineeringHydrogelsNanomedicineRegenerative MedicineEngineering +11

SEL1L–HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool

Yewei Ji, Yuan Luo, Yating Wu, +21

Nature Cell Biology

Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling

Neha Shrestha, Tongyu Liu, Yewei Ji, +13

Journal of Clinical Investigation

β Cell MaturationImmune RegulationCell DeathInsulin SignalingCell Autophagy +17

The obesity-induced adipokine sST2 exacerbates adipose T _reg and ILC2 depletion and promotes insulin resistance

Xu-Yun Zhao, Linkang Zhou, Zhimin Chen, +5

Science Advances

The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development

Yewei Ji, Hana Kim, Yang Liu, +4

Cell Reports

Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity

Yewei Ji, Shengyi Sun, Neha Shrestha, +15

Nature Immunology

InflammationMetabolic SyndromeObesityToll-like ReceptorsImmunology +9