Chun Deng

AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies

Sonya Zabludoff, Chun Deng, Michael Grondine et al. · Molecular Cancer Therapeutics · 2008 · 407 citations · Full text

Cell Death, Cell Cycle, Cancer Biology +17

Decreased ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients

Chun Deng, Mariana J. Kaplan, Donna Ray et al. · Arthritis & Rheumatism · 2001 · 252 citations · Full text

Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors

Kurt Oelke, Qianjin Lu, Derek Richardson et al. · Arthritis & Rheumatism · 2004 · 238 citations · Full text

Discovery of Checkpoint Kinase Inhibitor (<i>S</i>)-5-(3-Fluorophenyl)-<i>N</i>-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas

Vibha Oza, Susan Ashwell, Lynsie Almeida et al. · Journal of Medicinal Chemistry · 2012 · 67 citations · Full text

Drug Target, Molecular Biology, Chemical Biology +20

β-Cryptoxanthin induced anti-proliferation and apoptosis by G0/G1 arrest and AMPK signal inactivation in gastric cancer

Meili Gao, Fan Dang, Chun Deng · European Journal of Pharmacology · 2019 · 47 citations

Ampk Signal Inactivation, Gastrointestinal Oncology, Medicine +8