Simon Kirby

Candidate biomarkers for the diagnosis and prognosis of drug‐induced liver injury: An international collaborative effort

Rachel J. Church, Gerd A. Kullak‐Ublick, Jiri Aubrecht et al. · Hepatology · 2018 · 231 citations · Full text

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia

Lishuang Cao, Aoibhinn McDonnell, Anja Nitzsche et al. · Science Translational Medicine · 2016 · 195 citations

Efficacy of the Nav1.7 blocker PF-05089771 in a randomised, placebo-controlled, double-blind clinical study in subjects with painful diabetic peripheral neuropathy

Aoibhinn McDonnell, Susie M. Collins, Zahid Ali et al. · Pain · 2018 · 158 citations

Pain Therapy, Pain Medicine, Neuropathic Pain +20

A Quantitative Approach for Making Go/No-Go Decisions in Drug Development

Christy Chuang‐Stein, Simon Kirby, Jonathan French et al. · Drug Information Journal · 2011 · 57 citations

Drug Repositioning, Go/no-go Decisions, Drug Design +8

The role of the minimum clinically important difference and its impact on designing a trial

Christy Chuang‐Stein, Simon Kirby, Ian Hirsch et al. · Pharmaceutical Statistics · 2010 · 52 citations

Clinical Decision-making, Patient Selection, Clinical Endpoint +18