NICHOLAS B. LYDON

The angiotensin AT2 receptor stimulates protein tyrosine phosphatase activity and mediates inhibition of particulate guanylate cyclase

Serge P. Bottari, Isabelle N. King, Serge Reichlin et al. · Biochemical and Biophysical Research Communications · 1992 · 253 citations

Life Sciences, Biochemistry, Pharmacology +15

A precision therapy against cancers driven by <i>KIT/PDGFRA</i> mutations

Erica Evans, Alexandra K. Gardino, Joseph L. Kim et al. · Science Translational Medicine · 2017 · 214 citations

Medicine, Oncology, Pharmacology +10

The Structure-Based Design of ATP-Site Directed Protein KinaseInhibitors

Leticia M. Toledo, NICHOLAS B. LYDON, Daniel Elbaum · Current Medicinal Chemistry · 1999 · 175 citations

Pharmacy, Medicinal Chemistry, Oncology +15

Paeciloquinones A,B,C,D,E and F: New Potent Inhibitors of Protein Tyrosine Kinases Produced by Paecilomyces carneus. I. Taxonomy, Fermentation, Isolation and Biological Activity.

Frank Petersen, Andreas Fredenhagen, Helmut Mett et al. · The Journal of Antibiotics · 1995 · 29 citations · Full text

Life Sciences, Biochemistry, Pharmacology +9

ChemInform Abstract: Potent and Selective Inhibitors of the AbL‐Kinase: Phenylaminopyrimidine (PAP) Derivatives.

J. Zimmermann, Elisabeth Buchdunger, Helmut Mett et al. · ChemInform · 1997 · 25 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11