Lisa M. Anderson

An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes

Amber L. Southwell, Amy Smith-Dijak, Chris Kay et al. · Human Molecular Genetics · 2016 · 138 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Huntingtin suppression restores cognitive function in a mouse model of Huntington’s disease

Amber L. Southwell, Holly Kordasiewicz, Douglas R. Langbehn et al. · Science Translational Medicine · 2018 · 123 citations · Full text

Life Sciences, Genetics, Neuroscience +15

Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease

Costanza Ferrari Bardile, Marta Garcia‐Miralles, Nicholas S. Caron et al. · Proceedings of the National Academy of Sciences · 2019 · 120 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease

Nicholas S. Caron, Amber L. Southwell, Cynthia Brouwers et al. · Nucleic Acids Research · 2019 · 73 citations · Full text

Life Sciences, Neurology, Neuroscience +17

HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo

Dagmar E. Ehrnhoefer, Amber L. Southwell, Meenalochani Sivasubramanian et al. · Human Molecular Genetics · 2017 · 38 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17