Jerry Jeffrey

Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Brian A. Johns, Takashi Kawasuji, Jason G. Weatherhead et al. · Journal of Medicinal Chemistry · 2013 · 184 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore

Brian A. Johns, Jason G. Weatherhead, Scott H. Allen et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 114 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2−/−γC−/− mice in vivo

Qi Jiang, Liguo Zhang, Rui Wang et al. · Blood · 2008 · 104 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

1,3,4-Oxadiazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 2: SAR of the C5 position

Brian A. Johns, Jason G. Weatherhead, Scott H. Allen et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 92 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Allosteric Inhibition of Human Immunodeficiency Virus Integrase

Kushol Gupta, Troy Brady, Benjamin Dyer et al. · Journal of Biological Chemistry · 2014 · 81 citations · Full text

Life Sciences, Microbiology, Molecular Biology +13