An Ning Cheng

Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1–mediated immunoescape via STING-IFN signaling and extracellular vesicles

An Ning Cheng, Li-Chun Cheng, Cheng‐Liang Kuo et al. · Journal for ImmunoTherapy of Cancer · 2020 · 192 citations · Full text

Life Sciences, Immunology, Oncology +17

Mitochondrial oxidative stress by Lon-PYCR1 maintains an immunosuppressive tumor microenvironment that promotes cancer progression and metastasis

Cheng‐Liang Kuo, Han-Yu Chou, Yi-Chieh Chiu et al. · Cancer Letters · 2020 · 155 citations · Full text

Medicine, Cancer Biology, Oncology +17

Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity

Ya-Ju Sung, Ting‐Yu Kao, Cheng‐Liang Kuo et al. · Cell Death and Disease · 2018 · 58 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Dbf4 Is Direct Downstream Target of Ataxia Telangiectasia Mutated (ATM) and Ataxia Telangiectasia and Rad3-related (ATR) Protein to Regulate Intra-S-phase Checkpoint

Alan Yueh‐Luen Lee, Takuya Chiba, Lan N. Truong et al. · Journal of Biological Chemistry · 2011 · 53 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents

An Ning Cheng, Shih Sheng Jiang, Chi-Chen Fan et al. · Cancer Letters · 2013 · 51 citations

Medicine, Molecular Biology, Oncology +10