Cheng‐Liang Kuo

Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1–mediated immunoescape via STING-IFN signaling and extracellular vesicles

An Ning Cheng, Li-Chun Cheng, Cheng‐Liang Kuo et al. · Journal for ImmunoTherapy of Cancer · 2020 · 192 citations · Full text

Life Sciences, Immunology, Oncology +17

Mitochondrial oxidative stress by Lon-PYCR1 maintains an immunosuppressive tumor microenvironment that promotes cancer progression and metastasis

Cheng‐Liang Kuo, Han-Yu Chou, Yi-Chieh Chiu et al. · Cancer Letters · 2020 · 155 citations · Full text

Medicine, Cancer Biology, Oncology +17

Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity

Ya-Ju Sung, Ting‐Yu Kao, Cheng‐Liang Kuo et al. · Cell Death and Disease · 2018 · 58 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

SoxB1 transcription factors restrict organizer gene expression by repressing multiple events downstream of Wnt signalling

Yu-Huan Shih, Cheng‐Liang Kuo, Caroline S. Hirst et al. · Development · 2010 · 38 citations

Life Sciences, Biology, Developmental Biology +17

Mitochondrial Lon-induced mitophagy benefits hypoxic resistance via Ca2+-dependent FUNDC1 phosphorylation at the ER-mitochondria interface

Ananth Ponneri Babuharisankar, Cheng‐Liang Kuo, Han-Yu Chou et al. · Cell Death and Disease · 2023 · 37 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17