Han-Yu Chou

Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1–mediated immunoescape via STING-IFN signaling and extracellular vesicles

An Ning Cheng, Li-Chun Cheng, Cheng‐Liang Kuo et al. · Journal for ImmunoTherapy of Cancer · 2020 · 192 citations · Full text

Life Sciences, Immunology, Oncology +17

Mitochondrial oxidative stress by Lon-PYCR1 maintains an immunosuppressive tumor microenvironment that promotes cancer progression and metastasis

Cheng‐Liang Kuo, Han-Yu Chou, Yi-Chieh Chiu et al. · Cancer Letters · 2020 · 155 citations · Full text

Medicine, Cancer Biology, Oncology +17

Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity

Ya-Ju Sung, Ting‐Yu Kao, Cheng‐Liang Kuo et al. · Cell Death and Disease · 2018 · 58 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Mitochondrial Lon-induced mitophagy benefits hypoxic resistance via Ca2+-dependent FUNDC1 phosphorylation at the ER-mitochondria interface

Ananth Ponneri Babuharisankar, Cheng‐Liang Kuo, Han-Yu Chou et al. · Cell Death and Disease · 2023 · 37 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Lon upregulation contributes to cisplatin resistance by triggering NCLX-mediated mitochondrial Ca2+ release in cancer cells

Vidhya Tangeda, Yu Kang Lo, Ananth Ponneri Babuharisankar et al. · Cell Death and Disease · 2022 · 32 citations · Full text

Medicine, Cancer Biology, Oncology +17