Hua Rong Lu

International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment

Ksenia Blinova, Qianyu Dang, Daniel Millard et al. · Cell Reports · 2018 · 358 citations · Full text

Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology

Oliver J. Britton, Alfonso Bueno‐Orovio, Karel Van Ammel et al. · Proceedings of the National Academy of Sciences · 2013 · 325 citations · Full text

Cardiac Muscle, Engineering, Cardiovascular Function +19

Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity

Elisa Passini, Oliver J. Britton, Hua Rong Lu et al. · Frontiers in Physiology · 2017 · 316 citations · Full text

Predicting drug‐induced changes in QT interval and arrhythmias: QT‐shortening drugs point to gaps in the ICHS7B Guidelines

Hua Rong Lu, Eddy Vlaminckx, An N. Hermans et al. · British Journal of Pharmacology · 2008 · 130 citations · Full text

A new biomarker – index of Cardiac Electrophysiological Balance (iCEB) – plays an important role in drug-induced cardiac arrhythmias: beyond QT-prolongation and Torsades de Pointes (TdPs)

Hua Rong Lu, Gan‐Xin Yan, David J. Gallacher · Journal of Pharmacological and Toxicological Methods · 2013 · 123 citations

Cardiac Muscle, Cardiomyopathy, Important Role +12