Hua Rong Lu

International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment

Ksenia Blinova, Qianyu Dang, Daniel Millard et al. · Cell Reports · 2018 · 370 citations · Full text

Medicine, Cardiology, Pharmacology +16

Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity

Elisa Passini, Oliver J. Britton, Hua Rong Lu et al. · Frontiers in Physiology · 2017 · 333 citations · Full text

Medicine, Cardiology, Pharmacology +16

Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology

Oliver J. Britton, Alfonso Bueno‐Orovio, Karel Van Ammel et al. · Proceedings of the National Academy of Sciences · 2013 · 331 citations · Full text

Life Sciences, Cardiology, Physiology +16

Predicting drug‐induced changes in QT interval and arrhythmias: QT‐shortening drugs point to gaps in the ICHS7B Guidelines

Hua Rong Lu, Eddy Vlaminckx, An N. Hermans et al. · British Journal of Pharmacology · 2008 · 130 citations · Full text

Medicine, Cardiology, Pharmacology +17

A new biomarker – index of Cardiac Electrophysiological Balance (iCEB) – plays an important role in drug-induced cardiac arrhythmias: beyond QT-prolongation and Torsades de Pointes (TdPs)

Hua Rong Lu, Gan‐Xin Yan, David J. Gallacher · Journal of Pharmacological and Toxicological Methods · 2013 · 128 citations

Medicine, Cardiology, Pharmacology +15