David J. Gallacher

Predicting drug‐induced changes in QT interval and arrhythmias: QT‐shortening drugs point to gaps in the ICHS7B Guidelines

Hua Rong Lu, Eddy Vlaminckx, An N. Hermans et al. · British Journal of Pharmacology · 2008 · 130 citations · Full text

A new biomarker – index of Cardiac Electrophysiological Balance (iCEB) – plays an important role in drug-induced cardiac arrhythmias: beyond QT-prolongation and Torsades de Pointes (TdPs)

Hua Rong Lu, Gan‐Xin Yan, David J. Gallacher · Journal of Pharmacological and Toxicological Methods · 2013 · 123 citations

Cardiac Muscle, Cardiomyopathy, Important Role +12

In vivo mechanisms precipitating torsades de pointes in a canine model of drug-induced long-QT1 syndrome

David J. Gallacher, A VANDEWATER, H VANDERLINDE et al. · Cardiovascular Research · 2007 · 113 citations

Evaluation of Index of Cardio‐Electrophysiological Balance (iCEB) as a New Biomarker for the Identification of Patients at Increased Arrhythmic Risk

Tomas Robyns, Hua Rong Lu, David J. Gallacher et al. · Annals of Noninvasive Electrocardiology · 2015 · 111 citations · Full text

Best practice in the conduct of key nonclinical cardiovascular assessments in drug development: Current recommendations from the Safety Pharmacology Society

D.J. Leishman, Thomas W. Beck, Noël Dybdal et al. · Journal of Pharmacological and Toxicological Methods · 2011 · 103 citations

Cardiovascular Toxicity, Hypertension, Cardiovascular Disease +11