Wei Lu

Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036

Wayne W. Chan, Scott Wise, Michael D. Kaufman et al. · Cancer Cell · 2011 · 207 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 Inhibitor

Justin A. Caravella, Jian Lin, R. Bruce Diebold et al. · Journal of Medicinal Chemistry · 2020 · 144 citations · Full text

Pharmacy, Oncology, Pharmacology +15

Ultrahigh-Q Quasi-BICs via Precision-Controlled Asymmetry in Dielectric Metasurfaces

Mimi Zhou, Zhenchu Fu, Haoxuan He et al. · Nano Letters · 2025 · 79 citations

Natural Sciences, Materials Science, Physics +16

Synthesis, crystal structure and biological evaluation of substituted quinazolinone benzoates as novel antituberculosis agents targeting acetohydroxyacid synthase

Wei Lu, Huijie Sun, Changjun Cui et al. · European Journal of Medicinal Chemistry · 2015 · 59 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Inhibition of fatty acid synthase with <scp>FT‐4101</scp> safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non‐alcoholic fatty liver disease: Results from two early‐phase randomized trials

Carine Beysen, Patricia Schroeder, Eric Wu et al. · Diabetes Obesity and Metabolism · 2020 · 53 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +15