Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

E. John Wherry, Sang‐Jun Ha, Susan M. Kaech, +7

Immunity

Viral PersistenceHuman RetrovirusImmunologyAntiviral ResponseVirology +7

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

Surojit Sarkar, Vandana Kalia, W. Nicholas Haining, +3

The Journal of Experimental Medicine

Adaptive Immune SystemEffector SubsetsImmunologyImmune RegulationImmunologic Mechanism +17

Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

Vandana Kalia, Surojit Sarkar, Shruti Subramaniam, +3

Immunity

Adaptive Immune SystemImmunologyImmunologic MechanismT Cell ImmunityCd4 T Cell Responses +7

Strength of Stimulus and Clonal Competition Impact the Rate of Memory CD8 T Cell Differentiation

Surojit Sarkar, Volker Teichgräber, Vandana Kalia, +5

The Journal of Immunology

Quiescence of Memory CD8+ T Cells Is Mediated by Regulatory T Cells through Inhibitory Receptor CTLA-4

Vandana Kalia, Laura A. Penny, Yevgeniy Yuzefpolskiy, +2

Immunity

Signal TransductionAutoimmune DiseaseMedicineT-regulatory CellImmunology +7

Interleukin-21 Is a Critical Cytokine for the Generation of Virus-Specific Long-Lived Plasma Cells

Mohammed Ata Ur Rasheed, Donald R. Latner, Rachael D. Aubert, +11

Journal of Virology

Humoral ResponseImmunologyImmunologic MechanismImmunotherapyInflammation +15

MicroRNA-17∼92 regulates effector and memory CD8 T-cell fates by modulating proliferation in response to infections

Arif A. Khan, Laura A. Penny, Yevgeniy Yuzefpolskiy, +2

Blood

CD8 T-Cell Memory Differentiation during Acute and Chronic Viral Infections

Vandana Kalia, Surojit Sarkar, Rafi Ahmed

Advances in experimental medicine and biology

ImmunologyAntiviral ResponseVirologyChronic Viral InfectionsAutoimmunity +6

CCR10 regulates balanced maintenance and function of resident regulatory and effector T cells to promote immune homeostasis in the skin

Mingcan Xia, Shaomin Hu, Yaoyao Fu, +8

Journal of Allergy and Clinical Immunology

InflammationImmune HomeostasisImmune Effector FunctionsAutoimmune DiseaseT-regulatory Cell +9

Rational Site-Directed Mutations of the LLP-1 and LLP-2 Lentivirus Lytic Peptide Domains in the Intracytoplasmic Tail of Human Immunodeficiency Virus Type 1 gp41 Indicate Common Functions in Cell-Cell Fusion but Distinct Roles in Virion Envelope Incorporation

Vandana Kalia, Surojit Sarkar, Phalguni Gupta, +1

Journal of Virology

Virus StructureViral ReplicationRational Site-directed MutationsHuman RetrovirusImmunology +13