Concepedia

Shigeki Higashiyama

SH

Statistics

Publications

225

Citations

18.3K

H-Index

68

Active since

1986

Affiliations

Ehime University(Current)

The University of Osaka

Osaka International Cancer Institute

Nagoya City University

Shigeki Higashiyama is an author at Ehime University specializing in life sciences, cell signaling, and growth factor signaling.

ORCID

Publications per year

1986–2025

225

Publications

225

A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

Shigeki Higashiyama, Judith A. Abraham, John C. Fiddes et al. · Science · 1991 · 1.1K citations

, , +14

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

Umut Şahin, Gisela Weskamp, Kristine Kelly et al. · The Journal of Cell Biology · 2004 · 986 citations

, , +11

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

Masanori Asakura, Masafumi Kitakaze, Seiji Takashima et al. · Nature Medicine · 2002 · 718 citations

, , +7

TGFα shedding assay: an accurate and versatile method for detecting GPCR activation

Asuka Inoue, Jun Ishiguro, Hajime Kitamura et al. · Nature Methods · 2012 · 370 citations

, , +4

Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate

Shigeki Higashiyama, JA Abraham, Michael Klagsbrun · The Journal of Cell Biology · 1993 · 364 citations · Full text

, , +12

1–5 of 225