William S. Chen

Visualizing structure and transitions in high-dimensional biological data

Kevin R. Moon, David van Dijk, Zheng Wang et al. · Nature Biotechnology · 2019 · 1.1K citations · Full text

High-dimensional Biological Data, Engineering, Computational Biology +6

The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

Daniel C. Weinstein, Ariel Ruiz i Altaba, William S. Chen et al. · Cell · 1994 · 785 citations

Transcriptional Regulation, Developmental Biology, Notochord Development +10

Expression Cloning of Human EGF Receptor Complementary DNA: Gene Amplification and Three Related Messenger RNA Products in A431 Cells

Chijen R. Lin, William S. Chen, Wiebe Kruiger et al. · Science · 1984 · 406 citations

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

William S. Chen, Cheri S. Lazar, Kirk A. Lund et al. · Cell · 1989 · 355 citations

Ligand-induced Internalization, Developmental Biology, Signal Transduction +11

Exploring single-cell data with deep multitasking neural networks

Matthew Amodio, David van Dijk, Krishnan Srinivasan et al. · Nature Methods · 2019 · 346 citations · Full text

Single-cell Data, Engineering, Machine Learning +8