Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

J. Garnier, David J. Osguthorpe, Barry Robson · Journal of Molecular Biology · 1978 · 4.6K citations

Life Sciences, Biochemistry, Biophysics +13

Prediction of protein conformation

Peter Y. Chou, Gerald D. Fasman · Biochemistry · 1974 · 3.3K citations

Life Sciences, Biochemistry, Bioinformatics +9

Firefly luciferase gene: structure and expression in mammalian cells.

Jeffrey R. de Wet, Keith V. Wood, M. DeLuca et al. · Molecular and Cellular Biology · 1987 · 3.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

A Ullrich, Lisa M. Coussens, Joel S. Hayflick et al. · Nature · 1984 · 2.8K citations

Life Sciences, Genetics, Molecular Biology +7