YUSUKE AOKI

Linkage of methionine addiction, histone lysine hypermethylation, and malignancy

Jun Yamamoto, Sachiko Inubushi, Qinghong Han et al. · iScience · 2022 · 57 citations · Full text

Medicine, Cancer Biology, Oncology +14

Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation

YUSUKE AOKI, Qinghong Han, Yasunori Tome et al. · Frontiers in Oncology · 2022 · 50 citations · Full text

Medicine, Cancer Biology, Oncology +17

Extent and Instability of Trimethylation of Histone H3 Lysine Increases With Degree of Malignancy and Methionine Addiction

Jun Yamamoto, YUSUKE AOKI, Sachiko Inubushi et al. · Cancer Genomics & Proteomics · 2021 · 49 citations · Full text

Medicine, Cancer Biology, Oncology +16

Long-term Stable Disease in a Rectal-cancer Patient Treated by Methionine Restriction With Oral Recombinant Methioninase and a Low-methionine Diet

Yutaro Kubota, Qinghong Han, Kazuyuki Hamada et al. · Anticancer Research · 2022 · 49 citations · Full text

Medicine, Nutrition, Oncology +15

Stage IV Pancreatic Cancer Patient Treated With FOLFIRINOX Combined With Oral Methioninase: A Highly-Rare Case With Long-term Stable Disease

Yutaro Kubota, Qinghong Han, CHIHIRO HOZUMI et al. · Anticancer Research · 2022 · 40 citations · Full text

Medicine, Oncology, Pharmacology +14