Toshihiro Nishimura

The importance of CH/π hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase

Tomonaga Ozawa, Eiichi Tsuji, Motoyasu Ozawa et al. · Bioorganic & Medicinal Chemistry · 2008 · 74 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +14

Synthesis and c-Src inhibitory activity of imidazo[1,5-a]pyrazine derivatives as an agent for treatment of acute ischemic stroke

Harunobu Mukaiyama, Toshihiro Nishimura, Satoko Kobayashi et al. · Bioorganic & Medicinal Chemistry · 2006 · 54 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Novel pyrazolo[1,5-a]pyrimidines as c-Src kinase inhibitors that reduce IKr channel blockade

Harunobu Mukaiyama, Toshihiro Nishimura, Satoko Kobayashi et al. · Bioorganic & Medicinal Chemistry · 2007 · 44 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Discovery of Novel 2-Anilinopyrazolo[1,5-a]pyrimidine Derivatives as c-Src Kinase Inhibitors for the Treatment of Acute Ischemic Stroke

Harunobu Mukaiyama, Toshihiro Nishimura, Hiroaki Shiohara et al. · Chemical and Pharmaceutical Bulletin · 2007 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Asymmetric Total Synthesis of TaxolR

Teruaki Mukaiyama, Isamu Shiina, Hayato Iwadare et al. · Chemistry - A European Journal · 1999 · 24 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7