Concepedia

Novel pyrazolo[1,5-a]pyrimidines as c-Src kinase inhibitors that reduce IKr channel blockade

Harunobu Mukaiyama, Toshihiro Nishimura, Satoko Kobayashi, Yoshimitsu Komatsu, Shinji Kikuchi, Tomonaga Ozawa, Noboru Kamada, Hideki Ohnota

Bioorganic & Medicinal Chemistry · 2007 · 44 citations · 22 references

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22

The Structure of the Potassium Channel: Molecular Basis of K <sup>+</sup> Conduction and Selectivity

D. Doyle, João H. Morais‐Cabral, Richard A. Pfuetzner et al. · Science · 1998 · 6.8K citations

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MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia

Geoffrey W. Abbott, Federico Sesti, Igor Splawski et al. · Cell · 1999 · 1.4K citations · Full text

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VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

Zheng Gang Zhang, Li Zhang, Quan Jiang et al. · Journal of Clinical Investigation · 2000 · 1.3K citations · Full text

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A structural basis for drug-induced long QT syndrome

John S. Mitcheson, Jun Chen, Monica Lin et al. · Proceedings of the National Academy of Sciences · 2000 · 937 citations

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Selective Requirement for Src Kinases during VEGF-Induced Angiogenesis and Vascular Permeability

Brian P. Eliceiri, Robert Paul, Pamela L. Schwartzberg et al. · Molecular Cell · 1999 · 817 citations · Full text

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