Chunning Yang

Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1+ Activated T Cells

Simon J. Dovedi, Matthew J. Elder, Chunning Yang et al. · Cancer Discovery · 2021 · 180 citations

Life Sciences, Immunology, Oncology +17

Improving target cell specificity using a novel monovalent bispecific IgG design

Yariv Mazor, Vaheh Oganesyan, Chunning Yang et al. · mAbs · 2015 · 152 citations · Full text

Pharmacy, Biotechnology, Medicinal Chemistry +17

Enhanced tumor-targeting selectivity by modulating bispecific antibody binding affinity and format valence

Yariv Mazor, Kris F. Sachsenmeier, Chunning Yang et al. · Scientific Reports · 2017 · 123 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17

Insights into the molecular basis of a bispecific antibody's target selectivity

Yariv Mazor, Anna M. Hansen, Chunning Yang et al. · mAbs · 2015 · 82 citations · Full text

Pharmacy, Immunology, Molecular Biology +17

Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen

Bo Wang, Chunning Yang, Xiaofang Jin et al. · mAbs · 2019 · 63 citations · Full text

Life Sciences, Immunology, Molecular Biology +17