Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1+ Activated T Cells

Simon J. Dovedi, Matthew J. Elder, Chunning Yang, +32

Cancer Discovery

Functional interrogation and mining of natively paired human VH:VL antibody repertoires

Bo Wang, Brandon J. DeKosky, Morgan R. Timm, +30

Nature Biotechnology

ImmunogeneticsAutoimmune DiseaseHuman Leukocyte AntigenHuman VhMedicine +12

A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes

Xi Wang, Kristina G. Maxwell, Kai Wang, +14

Science Translational Medicine

Tissue EngineeringEngineeringBiomaterials DesignBiofabricationBiomedical Engineering +24

An in situ hydrogel-mediated chemo-immunometabolic cancer therapy

Bo Wang, Jing Chen, Julia S. Caserto, +2

Nature Communications

A Zwitterionic Polyurethane Nanoporous Device with Low Foreign‐Body Response for Islet Encapsulation

Qingsheng Liu, Xi Wang, Alan Chiu, +9

Advanced Materials

Tissue EngineeringZpu Encapsulation DeviceEngineeringPolymer NanotechnologyNanoporous Material +16

Development of humanized tri-specific nanobodies with potent neutralization for SARS-CoV-2

Jianbo Dong, Betty Huang, Bo Wang, +6

Scientific Reports

Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen

Bo Wang, Chunning Yang, Xiaofang Jin, +4

mAbs

Antibody-mediated Complement ActivationImmunocytochemical TechniqueImmunologyAntibody-mediated Complement-dependent CytotoxicityAntigen Processing +18

An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation

Jing Chen, Julia S. Caserto, Ida Ang, +6

Bioactive Materials

Engineered immunomodulatory accessory cells improve experimental allogeneic islet transplantation without immunosuppression

Xi Wang, Kai Wang, Ming Yu, +7

Science Advances

Sustained Delivery of SARS‐CoV‐2 RBD Subunit Vaccine Using a High Affinity Injectable Hydrogel Scaffold

Jing Chen, Bo Wang, Julia S. Caserto, +5

Advanced Healthcare Materials