Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1+ Activated T Cells

Simon J. Dovedi, Matthew J. Elder, Chunning Yang, +32

Cancer Discovery

A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells

Heather K. Kroh, Ramyavardhanee Chandrasekaran, Zhifen Zhang, +9

Journal of Biological Chemistry

Microbial ToxinNeutralizing AntibodyEnzymatic CargoToxinologyPathogenesis +8

Nrf2 knockout altered brain iron deposition and mitigated age-related motor dysfunction in aging mice

Kang Min Han, Xiaofang Jin, Xin Guo, +7

Free Radical Biology and Medicine

Neurodegenerative DiseasesAlzheimer's DiseaseAgingPhysiologyNrf2 Knockout +8

Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen

Bo Wang, Chunning Yang, Xiaofang Jin, +4

mAbs

Antibody-mediated Complement ActivationImmunocytochemical TechniqueImmunologyAntibody-mediated Complement-dependent CytotoxicityAntigen Processing +18

A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non–EGFR-Mediated Pathways

Jonathan Rios‐Doria, Darrin Sabol, Jon Chesebrough, +18

Molecular Cancer Therapeutics

Novel Adam17MedicineImmunologyCancer Cell BiologyCell Proliferation +11

Melanoma imaging using 111In-, 86Y- and 68Ga-labeled CHX-A″-Re(Arg11)CCMSH

Lihui Wei, Xiuli Zhang, Fabio Gallazzi, +8

Nuclear Medicine and Biology

68Ga-labeled Chx-a″-reEngineeringMedical ImagingOncologic ImagingMelanoma +6

Transcriptional Analysis of Metabolic Pathways and Regulatory Mechanisms of Essential Oil Biosynthesis in the Leaves of Cinnamomum camphora (L.) Presl

Jiexi Hou, Jie Zhang, Beihong Zhang, +3

Frontiers in Genetics

Acute Hyperglycemia May Induce Renal Tubular Injury Through Mitophagy Inhibition

Jingyu Wang, Xiaodan Yue, Cheng Meng, +10

Frontiers in Endocrinology

Iron promotes neurological function recovery in mice with ischemic stroke through endogenous repair mechanisms

Xin Guo, Xiaofang Jin, Kang Min Han, +11

Free Radical Biology and Medicine

Neurological Function RecoveryCerebral Vascular RegulationStroke RehabilitationIschemic StrokeReperfusion Injury +12

Brain iron deficiency and affected contextual fear memory in mice with conditional Ferroportin1 ablation in the brain

Qiong Wu, Hao Qian, Haiyan Li, +6

The FASEB Journal

Contextual Fear MemoryBrain FunctionIron MetabolismAffective NeuroscienceIron Deficiency +22