Mutational Analysis of Bovine Viral Diarrhea Virus RNA-Dependent RNA Polymerase

Vicky C. H. Lai, C. Cheng Kao, Eric Ferrari, +5

Journal of Virology

Viral ReplicationAmino AcidsViral Polymerase StructureMolecular BiologyVirus Gene +14

The Amino-Terminal Domain of Bovine Viral Diarrhea Virus N^proProtein Is Necessary for Alpha/Beta Interferon Antagonism

Laura H. V. G. Gil, Israr-ul H. Ansari, Ventzislav Vassilev, +6

Journal of Virology

Viral ReplicationImmunologyViral PathogenesisAlpha/beta Interferon AntagonismInnate Immunity +16

Comparative Analysis of Anti-Hepatitis C Virus Activity and Gene Expression Mediated by Alpha, Beta, and Gamma Interferons

I. Wayne Cheney, Vicky C. H. Lai, Weidong Zhong, +6

Journal of Virology

Viral ReplicationIfn-mediated Gene ExpressionImmunologyGene Expression MediatedPathology +15

In Vitro RNA Replication Directed by Replicase Complexes Isolated from the Subgenomic Replicon Cells of Hepatitis C Virus

Vicky C. H. Lai, Shannon Dempsey, Johnson Y. N. Lau, +2

Journal of Virology

Synthesis of pyrrolo[2,3-d]pyrimidine nucleoside derivatives as potential anti-HCV agents

Chamakura V.N.S. Varaprasad, Kanda S. Ramasamy, Jean‐Luc Girardet, +5

Bioorganic Chemistry

Antiviral Drug DevelopmentOrganic ChemistryChemistryPharmacologyAntiviral Compound +1

Mutations in NS5B Polymerase of Hepatitis C Virus: Impacts on in Vitro Enzymatic Activity and Viral RNA Replication in the Subgenomic Replicon Cell Culture

I. Wayne Cheney, Suhaila Naim, Vicky C. H. Lai, +7

Virology

Viral Rna ReplicationViral ReplicationMolecular VirologyHepatitis C VirusViral Hepatitis +8

Canonical 3′-deoxyribonucleotides as a chain terminator for HCV NS5B RNA-dependent RNA polymerase

Jaehoon Shim, Gabry Larson, Vicky C. H. Lai, +2

Antiviral Research

Chain TerminatorViral ReplicationNucleic Acid ChemistryViral Polymerase StructureNatural Sciences +8

Generation and Characterization of a Hepatitis C Virus NS3 Protease-Dependent Bovine Viral Diarrhea Virus

Vicky C. H. Lai, Weidong Zhong, Angela Skelton, +5

Journal of Virology

Virus StructureViral ReplicationMolecular VirologyNatural SciencesPathogenesis +11

Establishment of a Subgenomic Replicon for Bovine Viral Diarrhea Virus in Huh-7 Cells and Modulation of Interferon-Regulated Factor 3-Mediated Antiviral Response

Nigel Horscroft, Dan Bellows, Israr-ul H. Ansari, +6

Journal of Virology

Parallel synthesis of pteridine derivatives as potent inhibitors for hepatitis C virus NS5B RNA-dependent RNA polymerase

Yili Ding, Jean‐Luc Girardet, Kenneth L. Smith, +5

Bioorganic & Medicinal Chemistry Letters

MedicinePteridine DerivativesAntiviral Drug DevelopmentAntiviral TherapyMolecular Biology +8