Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture

Rolf Renne, Weidong Zhong, Brian Herndier, +4

Nature Medicine

Molecular VirologyPathogenesisPathologyVirologyHerpesviruses +4

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

Shane Crotty, David Maag, Jamie J. Arnold, +5

Nature Medicine

Viral ReplicationRna Virus MutagenMolecular BiologyVirologyVirus Gene +2

Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation

Philipp Tropberger, Alexandre Mercier, Margaret Robinson, +3

Proceedings of the National Academy of Sciences

Histone ModificationsEpigenetic ChangeGeneticsImmunologyMolecular Biology +27

A Complex Translational Program Generates Multiple Novel Proteins from the Latently Expressed Kaposin (K12) Locus of Kaposi’s Sarcoma-Associated Herpesvirus

Robert H. Sadler, Lijun Wu, Bagher Forghani, +4

Journal of Virology

Complex Translational ProgramViral ReplicationImmunologyPathologySarcoma-associated Herpesvirus +21

De Novo Initiation of RNA Synthesis by Hepatitis C Virus Nonstructural Protein 5B Polymerase

Weidong Zhong, Annette S. Uss, Eric Ferrari, +2

Journal of Virology

Viral ReplicationRna ReplicationViral Polymerase MechanismMolecular BiologyViral Rna Genome +15

A Novel Mechanism to Ensure Terminal Initiation by Hepatitis C Virus NS5B Polymerase

Zhi Hong, Craig E. Cameron, Michelle Walker, +4

Virology

Novel MechanismViral ReplicationMolecular VirologyHepatitis CViral Hepatitis +9

Identification of a previously undescribed divergent virus from the Flaviviridae family in an outbreak of equine serum hepatitis

Sanjay Chandriani, Peter Skewes-Cox, Weidong Zhong, +5

Proceedings of the National Academy of Sciences

Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides

Jamie J. Arnold, Suresh D. Sharma, Joy Y. Feng, +16

PLoS Pathogens

Discovery of the First <i>C</i>-Nucleoside HCV Polymerase Inhibitor (GS-6620) with Demonstrated Antiviral Response in HCV Infected Patients

Aesop Cho, Lijun Zhang, Jie Xu, +21

Journal of Medicinal Chemistry

Viral Polymerase StructureAdenosine AnalogsHepatitis C VirusImmunologyPharmacotherapy +15

De NovoInitiation of RNA Synthesis by a Recombinant Flaviridae RNA-dependent RNA Polymerase

C. Cheng Kao, Alfred M. Del Vecchio, Weidong Zhong

Virology

EngineeringViral Polymerase StructureNatural SciencesRna BiologyMolecular Biology +6