Yifang Huang

2-Amino-3,4-dihydroquinazolines as Inhibitors of BACE-1 (β-Site APP Cleaving Enzyme):  Use of Structure Based Design to Convert a Micromolar Hit into a Nanomolar Lead

Ellen W. Baxter, Kelly A. Conway, Ludo Kennis et al. · Journal of Medicinal Chemistry · 2007 · 145 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Hydrazinonaphthalene and Azonaphthalene Thrombopoietin Mimics Are Nonpeptidyl Promoters of Megakaryocytopoiesis

Kevin J. Duffy, Michael G. Darcy, Evelyne Delorme et al. · Journal of Medicinal Chemistry · 2001 · 121 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 1. Discovery and Optimization of Salicylaldehyde Thiosemicarbazone Thrombopoietin Mimics

Kevin J. Duffy, Anthony N. Shaw, Evelyne Delorme et al. · Journal of Medicinal Chemistry · 2002 · 87 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

The Efficient, Enantioselective Synthesis of Aza Sugars from Amino Acids. 1. The Polyhydroxylated Pyrrolidines

Yifang Huang, David R. Dalton, Patrick J. Carroll · The Journal of Organic Chemistry · 1997 · 77 citations

Natural Sciences, Biochemistry, Natural Product Biosynthesis +7

Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 2. Rational Design of Naphtho[1,2-<i>d</i>]imidazole Thrombopoietin Mimics

Kevin J. Duffy, Alan T. Price, Evelyne Delorme et al. · Journal of Medicinal Chemistry · 2002 · 59 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17