Kevin J. Duffy

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang et al. · Nature · 2018 · 803 citations

Systemic Activity, Medicine, Mechanism Of Action +4

Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells

Han Xie, Jun‐ichi Hanai, Jian-Guo Ren et al. · Cell Metabolism · 2014 · 507 citations · Full text

Oncology, Oncogenic Agent, Impacts Tumor-initiating Cells +8

Preclinical Activity of Eltrombopag (SB-497115), an Oral, Nonpeptide Thrombopoietin Receptor Agonist

Connie L. Erickson‐Miller, Evelyne Delorme, Shin‐Shay Tian et al. · Stem Cells · 2008 · 280 citations · Full text

Platelet Numbers, Immunology, Blood Cell +21

A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies

Harriet S. Walter, Simon A. Rule, Martin J.S. Dyer et al. · Blood · 2015 · 262 citations · Full text

Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells

Julia Billiard, Jennifer B. Dennison, Jacques Briand et al. · Cancer & Metabolism · 2013 · 231 citations · Full text