Accelerating Novel Candidate Gene Discovery in Neurogenetic Disorders via Whole-Exome Sequencing of Prescreened Multiplex Consanguineous Families

Anas M. Alazami, Nisha Patel, Hanan E. Shamseldin, +50

Cell Reports

Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef

Xiaofei Jia, Rajendra Singh, Stefanie Homann, +3

Nature Structural & Molecular Biology

MedicineHuman RetrovirusInnate Immune SystemImmunologyAntiviral Response +8

Structural insight into the mechanisms of enveloped virus tethering by tetherin

Haitao Yang, Jimin Wang, Xiaofei Jia, +7

Proceedings of the National Academy of Sciences

Tetherin Ectodomain DimersProtein AssemblyMolecular BiologyStructural InsightViral Structural Protein +14

Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1

Xiaofei Jia, Erin L. Weber, Andrey Tokarev, +5

eLife

The Crystal Structures of the Open and Catalytically Competent Closed Conformation of Escherichia coli Glycogen Synthase

Fang Sheng, Xiaofei Jia, Alejandra Yep, +2

Journal of Biological Chemistry

“Turn-On” Protein Fluorescence: In Situ Formation of Cyanine Dyes

Ipek Yapici, Kin Sing Stephen Lee, Tetyana Berbasova, +7

Journal of the American Chemical Society

Mutations in ASPH Cause Facial Dysmorphism, Lens Dislocation, Anterior-Segment Abnormalities, and Spontaneous Filtering Blebs, or Traboulsi Syndrome

Nisha Patel, Arif O. Khan, Ahmad M. Mansour, +8

The American Journal of Human Genetics

Developmental AnomalyOphthalmologyGenetic DisorderMedicineGenetics +4

Structural basis of CD4 downregulation by HIV-1 Nef

Yonghwa Kwon, Robyn M. Kaake, Ignacia Echeverria, +10

Nature Structural & Molecular Biology

MedicineHuman RetrovirusImmunologyAntiviral ResponseChronic Viral Infection +3

A Conserved Acidic-Cluster Motif in SERINC5 Confers Partial Resistance to Antagonism by HIV-1 Nef

Charlotte A. Stoneham, Peter W. Ramirez, Rajendra Singh, +6

Journal of Virology

Proteomic analysis of regenerating mouse liver following 50% partial hepatectomy

Hongcui Cao, Jiong Yu, Wei Xu, +9

Proteome Science