Stimulation of NF-κB Activity by the HIV Restriction Factor BST2

Andrey Tokarev, Marissa Suarez, Wilson Kwan, +3

Journal of Virology

Serine-Threonine Ubiquitination Mediates Downregulation of BST-2/Tetherin and Relief of Restricted Virion Release by HIV-1 Vpu

Andrey Tokarev, Jason Munguia, John Guatelli

Journal of Virology

Molecular RegulationHiv-1 VpuImmunologyImmune RegulationPotential Ubiquitination Sites +21

HIV-1 Vpu Protein Antagonizes Innate Restriction Factor BST-2 via Lipid-embedded Helix-Helix Interactions

Mark Skasko, Yan Wang, Ye Tian, +6

Journal of Biological Chemistry

Proteinlipid InteractionImmunologyMolecular BiologyInnate ImmunityAnalytical Ultracentrifugation +19

Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1

Xiaofei Jia, Erin L. Weber, Andrey Tokarev, +5

eLife

Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial

Trevor A. Crowell, Donn Colby, Suteeraporn Pinyakorn, +67

The Lancet HIV

Treatment And PreventionImmunotherapyHuman RetrovirusImmunologyAntiviral Therapy +5

BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: Evidence for a post-ER mechanism of Vpu-action

Mark Skasko, Andrey Tokarev, Cheng‐Chang Chen, +3

Virology

Post-er MechanismSignal TransductionViral PersistenceHuman RetrovirusImmunology +9

Misdirection of membrane trafficking by HIV-1 Vpu and Nef

Andrey Tokarev, John Guatelli

Cellular Logistics

Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge

Kier Om, Dominic Paquin‐Proulx, Maria Montero, +30

PLoS Pathogens

VaccinationMucosal VaccinationVaccine DevelopmentVaccine ResearchImmunology +12

Interferon-Induced SCYL2 Limits Release of HIV-1 by Triggering PP2A-Mediated Dephosphorylation of the Viral Protein Vpu

Kei Miyakawa, Tatsuya Sawasaki, Satoko Matsunaga, +8

Science Signaling

Viral ReplicationImmunologyMolecular BiologyPp2a-mediated DephosphorylationAntiviral Drug +14

Preferential Infection of α4β7+ Memory CD4+ T Cells During Early Acute Human Immunodeficiency Virus Type 1 Infection

Andrey Tokarev, Lyle R. McKinnon, Amélie Pagliuzza, +11

Clinical Infectious Diseases