Concepedia

Karen Chen

KC

Statistics

Publications

26

Citations

2.8K

H-Index

19

Active since

1987

Affiliations

Harvard University(Current)

PTC Therapeutics (United States)

Brigham and Women's Hospital

Neurological Surgery

Massachusetts General Hospital

Karen Chen is an author at Harvard University specializing in life sciences, neuroscience, and neurodegenerative disorders.

ORCID

Publications per year

1987–2025

26

Publications

26

A learning deficit related to age and β-amyloid plaques in a mouse model of Alzheimer's disease

Guiquan Chen, Karen Chen, Jane Knox et al. · Nature · 2000 · 740 citations

, , +16

<i>SMN2</i> splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

Nikolai A. Naryshkin, Marla Weetall, Amal Dakka et al. · Science · 2014 · 526 citations

, , +17

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

David M. Holtzman, Daniela Santucci, Joshua F. Kilbridge et al. · Proceedings of the National Academy of Sciences · 1996 · 451 citations · Full text

, , +17

Partial Reduction of BACE1 Has Dramatic Effects on Alzheimer Plaque and Synaptic Pathology in APP Transgenic Mice

Lisa McConlogue, Manuel Buttini, John P. Anderson et al. · Journal of Biological Chemistry · 2007 · 294 citations · Full text

, , +17

Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy

Hasane Ratni, Gary M. Karp, Marla Weetall et al. · Journal of Medicinal Chemistry · 2016 · 113 citations

, , +14

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