Sulin Zhang

Sequence-based drug design as a concept in computational drug design

Lifan Chen, Zisheng Fan, Jie Chang et al. · Nature Communications · 2023 · 107 citations · Full text

Drug Target, Engineering, Molecular Biology +21

Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations

Chuan Zhou, Zisheng Fan, Zehui Zhou et al. · Journal of Medicinal Chemistry · 2022 · 77 citations · Full text

SNX10‐mediated LPS sensing causes intestinal barrier dysfunction via a caspase‐5‐dependent signaling cascade

Xu Wang, Jiahui Ni, Yan You et al. · The EMBO Journal · 2021 · 71 citations · Full text

Inflammation, Signal Transduction, Mucosal Immunology +6

SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC

Sulin Zhang, Zhiwen Yang, Weilian Bao et al. · Autophagy · 2019 · 63 citations · Full text

Discovery of Pyrazolo[3,4- <i>d</i> ]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation

Xiaoqin Tan, Chunpu Li, Ruirui Yang et al. · Journal of Medicinal Chemistry · 2021 · 63 citations · Full text